Sjögren’s Syndrome is an autoimmune disease. Autoimmune diseases feature the abnormal production of extra antibodies in the blood directed against various tissues of the body, which tends to lead to inflammation. The hallmark symptom of Sjögren’s syndrome is generalized dryness, typically xerostomia (dry mouth) and keratoconjunctivitis sicca (dry eyes), known as sicca symptoms. Sjögren’s syndrome may cause skin, nose and vaginal dryness and may affect other organs of the body, including the kidneys, blood vessels, lungs, liver, pancreas, peripheral nervous system or brain.
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